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Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation (SPOT)
Sponsor: Centre Hospitalier Universitaire de Nice
Summary
Patient undergoing surgery is exposed to many stressors: diachronic (gesture anticipation), synchronic (intraoperative aggression) and historical (subject's personality). Reducing the level of stress experienced is a factor for improving the quality of the surgical gesture and the simplicity of the follow-up. The previous methods used were intended to reduce the body's reactivity to aggressions through anaesthesia consultation and L-Tyrosine supplementation. Currently with the progression of outpatient surgery and the need for early rehabilitation, L-Tyrosine supplementation is suppressed to improve recovery. Some patients, however, have a high level of stress that may require anxiolysis when the ideal treatment does not exist (ineffective hydroxyzine, benzodiazepines having many side effects). The strategy of this work is to improve the body's ability to respond to stressors, by administering l-tyrosine with no impact on waking or returning home.
Official title: Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2023-11-14
Completion Date
2026-05
Last Updated
2025-12-08
Healthy Volunteers
No
Conditions
Interventions
L-tyrosine supplementation
L-Tyrosine supplementation before surgery for inguinal hernia under general anaesthesia
Placebo supplementation
Placebo supplementation before surgery for inguinal hernia under general anaesthesia
Locations (1)
CHPG
Monaco, Monaco