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RECRUITING
NCT05782829
NA

Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation (SPOT)

Sponsor: Centre Hospitalier Universitaire de Nice

View on ClinicalTrials.gov

Summary

Patient undergoing surgery is exposed to many stressors: diachronic (gesture anticipation), synchronic (intraoperative aggression) and historical (subject's personality). Reducing the level of stress experienced is a factor for improving the quality of the surgical gesture and the simplicity of the follow-up. The previous methods used were intended to reduce the body's reactivity to aggressions through anaesthesia consultation and L-Tyrosine supplementation. Currently with the progression of outpatient surgery and the need for early rehabilitation, L-Tyrosine supplementation is suppressed to improve recovery. Some patients, however, have a high level of stress that may require anxiolysis when the ideal treatment does not exist (ineffective hydroxyzine, benzodiazepines having many side effects). The strategy of this work is to improve the body's ability to respond to stressors, by administering l-tyrosine with no impact on waking or returning home.

Official title: Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2023-11-14

Completion Date

2026-05

Last Updated

2025-12-08

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

L-tyrosine supplementation

L-Tyrosine supplementation before surgery for inguinal hernia under general anaesthesia

DIETARY_SUPPLEMENT

Placebo supplementation

Placebo supplementation before surgery for inguinal hernia under general anaesthesia

Locations (1)

CHPG

Monaco, Monaco