Clinical Research Directory

Inclusion Criteria: 1. Child is healthy at the time of pre-examination 2. Child is aged between 10-36 months and attends a day care center for the duration of the intervention 3. Child attends a daycare center at the time of pre examination for at least 50%. 4. Child presents a normal defecation characteristic (according to Brussels Infant and Toddler Stool scale) 5. Weight for height z-score \>-2 and \<2 SD based on Flemish growth charts 6. Child and legal guardian are able and willing to follow the study instructions 7. Child is suitable for participation in the study according to the investigator/ study personnel 8. Informed written consent given by parent / legal guardian Exclusion Criteria: 1. No legal guardian's command of any local language 2. Child with any chronic disorder or disease, e.g., defecation disorders (incl. Hirschsprung and celiac disease) metabolic or renal abnormalities as well as mental or psychomotor retardation (incl. child´s mental delay and hypotonia) 3. Child is suffering from congenital or acquired immunodeficiency 4. Food allergies or intolerances 5. Child is currently breast-fed more than once daily 6. Use of drugs (e.g. antibiotics) influencing gastrointestinal function (6 weeks before intervention) 7. Use of laxatives (4 weeks before intervention) as well as probiotic and prebiotic food supplements. Follow-on formula with L. Reuteri and/or GOS/FOS/HMO is allowed. 8. Child is suffering from an infection at the time of pre examination or previous 7 days 9. Child is currently involved or will be involved in another clinical or food study 10. Child is not suitable for participation in the study according to the study personnel´s opinion