Clinical Research Directory
Browse clinical research sites, groups, and studies.
Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence
Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago
Summary
This research study uses a cluster randomized controlled trial design to evaluate the effectiveness of Treatment Text (TXTXT) intervention on adherence and viral load suppression at 3- and 6- months post intervention initiation for youth and young adults with HIV. A total of 12 clinics will be randomized into one of the following two conditions: 1. Comparison Arm (n=6 clinics)- Clinics randomized to the comparison arm will have participants receive the standard of care for 3 months, followed by a 3-month intervention period. 2. Intervention Arm (n=6 clinics)- Clinics randomized to the intervention arm will have participants receive the TXTXT intervention for 6 months.
Key Details
Gender
All
Age Range
16 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
600
Start Date
2023-04-17
Completion Date
2025-08
Last Updated
2024-08-28
Healthy Volunteers
No
Conditions
Interventions
Treatment Text (TXTXT)
This study will test a tailored, personalized SMS text message reminder intervention to improve adherence to ART among non-adherent youth and young adults with HIV. Participants will use their own cell phones for receipt of the intervention. Participants will have the option to choose a tailored personalized message that may be changed as requested throughout the 6-month intervention period. Participants will be asked to send a text message response indicating that that have successfully (or not) taken their meds per schedule. No identifying patient information will be included in the SMS text to protect patient confidentiality.
Standard of Care
Standard of care ART adherence support includes adherence counseling during visits scheduled at least twice annually and appointment reminders.
Locations (12)
AIDS Healthcare Foundation
Fort Lauderdale, Florida, United States
University of Illinois at Chicago
Chicago, Illinois, United States
Howard Brown Health
Chicago, Illinois, United States
Eskenazi Health
Indianapolis, Indiana, United States
Indiana University
Indianapolis, Indiana, United States
Comprehensive Care Center of Southwest Louisiana
Lake Charles, Louisiana, United States
Corktown Health Center
Detroit, Michigan, United States
KC Care Health Center
Kansas City, Missouri, United States
Duke University
Durham, North Carolina, United States
University of Cincinnati
Cincinnati, Ohio, United States
Baylor College of Medicine
Houston, Texas, United States
Valley AIDS Council
McAllen, Texas, United States