Clinical Research Directory
Browse clinical research sites, groups, and studies.
Immunity to Infection in Healthy Participants and Participants With Cancer
Sponsor: University Hospital Tuebingen
Summary
Many cancer patients are highly susceptible to infection and respond poorly to vaccination. This observational study will determine molecular and cellular features of immunity to viral pathogens in participants with cancer and compare them to healthy controls. The aim is to identify how antiviral immunity in participants with cancer differs from that in healthy participants to understand why cancer patients are more susceptible to infections. In this context, the investigators will also evaluate immunity to medically indicated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and seasonal influenza vaccine received by study participants during standard care (vaccines are not part of the study).
Official title: Systems Biology Analysis of Vaccine-induced Immunity to Infectious Diseases in Healthy Participants and Participants With Cancer
Key Details
Gender
All
Age Range
18 Years - 90 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2022-10-01
Completion Date
2024-09-01
Last Updated
2024-05-09
Healthy Volunteers
Yes
Interventions
Biological sample collection
Whole blood (blood draw/phlebotomy) will be obtained to proceed with immunologic analysis of samples. Collection of biologic samples will occur up to 12 months.
Locations (1)
University Hopsital Tuebingen
Tübingen, Baden-Wurttemberg, Germany