Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT05788120

Incidence and Morbidity of Cardiac Rhythm Disorders in Patients Assisted by ECMO-VA for Refractory Cardiogenic Shock

Sponsor: Assistance Publique - Hôpitaux de Paris

View on ClinicalTrials.gov

Summary

Brief Summary : Rhythm disorders are a frequent and potentially serious complication of critical patients in the ICU and postoperative cardiac surgery. In particular, atrial fibrillation (AF) is the most common rhythm disorder in patients admitted to the ICU and is associated with excess mortality during acute circulatory failure. In postoperative cardiac surgery, AF affects 15 to 45% of patients. In addition to hemodynamic effects, AF increases the risk of stroke, bleeding, respiratory or renal failure, and doubles mortality at 30 days and 6 months. In the longer term, the recurrence rate of AF within 1 year after hospital discharge is about 50%. Similarly, other rhythm disorders, supraventricular or ventricular, can be life-threatening in ICU patients. While the incidence and complications of rhythm disorders are well documented during sepsis, cardiogenic shock or after cardiac surgery, there are to our knowledge no data on the frequency and complications of rhythm disorders in patients assisted by VA ECMO. The primary objective is to describe the incidence of supraventricular rhythm disorders in patients assisted by VA ECMO.

Official title: Incidence and Morbidity of Cardiac Rhythm Disorders in Patients Assisted by Extra Corporeal Membrane Oxygenation Veno-arterial (ECMO VA) for Refractory Cardiogenic Shock

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

600

Start Date

2023-04-28

Completion Date

2027-04-28

Last Updated

2025-12-09

Healthy Volunteers

No

Interventions

OTHER

Follow up by phone call

Centralized review of ECGs by the Pitié-Salpêtrière rhythmology department and collection of vital status at 12 months (if information not available, telephone call to the patient)

Locations (20)

CHU Angers

Angers, France

Hospices Civils de Lyon - Hôpital Louis Pradel

Bron, France

CHU Caen Normandie - Hôpital Côte de Nacre

Caen, France

CHRU Tours - Hôpital Trousseau

Chambray-lès-Tours, France

CHU Dijon Bourgogne - Hôpital François Mitterrand

Dijon, France

CHU Grenoble Alpes - Site Nord

Grenoble, France

CHU Lille - Institut Cœur Poumon

Lille, France

CHU Montpellier - Hôpital Arnaud de Villeneuve

Montpellier, France

CHU Nantes - Hôpital Nord Laennec

Nantes, France

Pitié Salpêtrière Hospital, Intensive Care Unit - Resuscitation

Paris, France

Pitié-Salpêtrière Hospital, Cardiovascular Surgery Intensive Care Unit

Paris, France

Hôpital Européen Georges Pompidou

Paris, France

Hôpital Bichat

Paris, France

Hôpital Bichat

Paris, France

CHU Bordeaux - Hôpital cardiologique, GH Sud Pessac

Pessac, France

CHU Rennes, Hôpital Pontchaillou

Rennes, France

Hôpitaux universitaires de Strasbourg - Hôpital Civil

Strasbourg, France

CHU Toulouse - Hôpital de Rangueil

Toulouse, France

CHU Toulouse - Hôpital de Rangueil

Toulouse, France

CHRU Nancy - Hôpitaux de Brabois

Vandœuvre-lès-Nancy, France