Clinical Research Directory
Browse clinical research sites, groups, and studies.
Implementing ctDNA and Circular DNA in Patients With Localized Pancreatic Cancer
Sponsor: Copenhagen University Hospital at Herlev
Summary
The goal of this clinical trial is to investigate if plasma ctDNA and eccDNA before resection for suspicion of pancreatic ductal adenocarcinoma (PDAC) can predict early recurrence and overall survival, and to investigate if plasma ctDNA combined with CT scan and endoscopic ultrasound surveillance increases the median overall survival compared with standard-of-care surveillance.
Official title: Implementing Non-invasive Circulating Tumor DNA and Circular DNA Analysis in Patients With Localized Pancreatic Cancer to Optimize the Pre- and Postoperative Treatment: Predicting Recurrence and Survival and Changing Prognosis Over Time
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
1000
Start Date
2023-01-01
Completion Date
2032-01
Last Updated
2026-03-27
Healthy Volunteers
No
Conditions
Interventions
ctDNA
ctDNA guided surveillance
Locations (5)
Aalborg Universitetshospital
Aalborg, Denmark
Aarhus Universitetshospital
Aarhus, Denmark
Copenhagen University Hospital - Rigshospitalet
Copenhagen, Denmark
Copenhagen University Hospital - Herlev and Gentofte
Herlev, Denmark
Odense Universitetshospital
Odense, Denmark