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NOT YET RECRUITING
NCT05792020
NA

Safety, Parameterization, and Mechanism of Transcranial Focused Ultrasound

Sponsor: Medical University of South Carolina

View on ClinicalTrials.gov

Summary

Through the BrainBox Initiative, investigators propose to study the effects of motor tFUS on Motor Evoked Potentials (MEPs) and GABA and Glutamate Concentrations in the Brain.

Official title: Safety, Parameterization, and Mechanism of Transcranial Focused Ultrasound (fUS) Over the Motor Cortex

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

25

Start Date

2026-05

Completion Date

2027-12-30

Last Updated

2026-02-27

Healthy Volunteers

Yes

Conditions

Interventions

DEVICE

Focused Ultrasound Stimulation

This aim will test whether motor tFUS parameters thought to be excitatory (50% duty cycle) vs. inhibitory (5% duty cycle) elicit their predicted effects on MEPs before and after each of three stimulation blocks, using 50 MEPs at each time point.

Locations (1)

Medical University of South Carolina

Charleston, South Carolina, United States