Clinical Research Directory

Inclusion Criteria: * Age between 18-65 years * Confirmed diagnosis of ankylosing spondylitis (AS) according to the modified New York criteria or the ASAS classification criteria for axial spondyloarthritis * Active disease at enrolment, confirmed by a PM\&R specialist * Written informed consent and compliance with the study protocol Exclusion Criteria: * Having received WCT within the previous 3 months * Contraindications to WCT (hemoglobin \<9.5 g/dL, known bleeding or coagulation disorders, anticoagulant use or antiplatelet therapy other than aspirin \<100 mg, INR \>1.5, etc.) * Pregnancy or breastfeeding * Severe uncontrolled comorbidities (e.g., advanced cardiovascular disease, uncontrolled diabetes, active malignancy, severe psychiatric illness) * Any change in AS medication during the study period * Failure to complete either baseline or follow-up visits