Clinical Research Directory

Inclusion Criteria: 1. 18≤ age ≤75, no gender limitation; 2. patients clinically diagnosed as acute pulmonary embolism requiring pulmonary artery thrombosis clearance; 3. RV/LV ratio ≥0.9; 4. Duration of pulmonary embolism symptoms ≤14 days 5. Systolic blood pressure ≥90mmHg 6. Patients who agreed to participate in the study and voluntarily signed the informed consent. Exclusion Criteria: 1. Target vessel diameter \< 6.6mm; 2. Calcification, plaque or stenosis of target lesions; 3. Pulmonary arterial hypertension with peak pulmonary arterial pressure \>70mmHg; 4. Vasopressor is required after infusion to maintain pressure ≥90mmHg; 5. Hematocrit \< 28%; 6. Patients with left bundle branch block; 7. A history of chronic left heart failure and left ventricular ejection fraction≤30%; 8. Patients with abnormal renal function (serum creatinine \> 1.8 mg/dL or \>159umol/L); 9. Patients with known coagulopathy or bleeding tendency (platelet\<100×109/L, or INR\> 3); 10. Patients who cannot receive antiplatelet or anticoagulant therapy; 11. Patients who underwent cardiovascular or pulmonary open surgery within 7 days before surgery; 12. Patients with intracardiac thrombosis; 13. Patients treated with extracorporeal membrane oxygenation; 14. Patients known to be allergic to contrast agents; 15. Patients with diseases that may cause difficulty in treatment and evaluation (such as malignant tumor, acute infectious disease, sepsis, general condition that cannot tolerate surgery, life expectancy less than 3 months, etc.); 16. Pregnant and lactating women; 17. Patients who are participating in clinical trials of other drugs or medical devices; 18. Other patients deemed unsuitable for the study by the investigator;