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The Role of Macrophage Activation in Lung Injury Following Ozone Exposure
Sponsor: Rutgers, The State University of New Jersey
Summary
The purpose of the study is to better understand the mechanisms of lung injury from ozone exposure. Subjects will participate in two exposure sessions: filtered air and 0.2 ppm ozone. The exposure visits will be at least 2 weeks apart. Subjects will be asked to produce sputum through coughing after each exposure. The samples will be analyzed for macrophage activity.
Official title: Activated Macrophages and Ozone Toxicity II
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2023-02-07
Completion Date
2027-06-01
Last Updated
2025-12-17
Healthy Volunteers
Yes
Conditions
Interventions
Clean Air
Subjects will be exposed to clean air for 3 hours.
Ozone
Subjects will be exposed to 0.2 ppm ozone for 3 hours.
Locations (1)
Rutgers - EOHSI
Piscataway, New Jersey, United States