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ACTIVE NOT RECRUITING
NCT05794646
NA

Community Intervention to Eliminate HCV Among People Who Use Drugs.

Sponsor: ANRS, Emerging Infectious Diseases

View on ClinicalTrials.gov

Summary

The goal of this interventional study is twofold with the evaluation of the feasibility and potential usefulness of an implementation strategy, and the efficiency of a community-based model of mass screening and immediate treatment of hepatitis C among People Who Use Drugs (PWUD) in three major cities in mainland France (Paris, Lyon and Marseille) and in one overseas city (Fort-de-France). The investigators will also describe the psychological and infectious comorbidities of drug users, determine the stages of the HCV (Hepatitis C Virus), HBV (Hepatitis B Virus), HIV (Human Immunodeficiency Virus) care cascade, and analyze the factors associated with HCV treatment failure. A qualitative study will investigate the acceptability of the RDS model. Participants will be screened in an out of bound research center and receive appropriate treatment for infectious, addictological and psychiatric troubles. They will receive coupons to give to their peers for them to participate in the study. Researchers will also compare the acceptability of referral to psychiatric care directly at the research site (intervention group) with that of referral directly to a city facility (control group).

Official title: Community Intervention to Eliminate HCV Among People Who Use Drugs. Implementation Study in the Cities of Paris, Marseille, Lyon and Fort-de-France, France.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

3400

Start Date

2023-10-02

Completion Date

2025-09-30

Last Updated

2025-09-08

Healthy Volunteers

Yes

Interventions

OTHER

Hybrid effectiveness-implementation study type 2

Diagnosis of hepatitis C; Assessment of hepatic fibrosis; Treatment of hepatitis C; Assessment of psychological disorders and treatment or referral.

Locations (4)

Lyon

Lyon, Auvergne-Rhône-Alpes, France

Marseille

Marseille, PACA, France

Paris

Paris, Île-de-France Region, France

Martinique

Fort-de-France, Martinique, Martinique