Clinical Research Directory
Browse clinical research sites, groups, and studies.
Community Intervention to Eliminate HCV Among People Who Use Drugs.
Sponsor: ANRS, Emerging Infectious Diseases
Summary
The goal of this interventional study is twofold with the evaluation of the feasibility and potential usefulness of an implementation strategy, and the efficiency of a community-based model of mass screening and immediate treatment of hepatitis C among People Who Use Drugs (PWUD) in three major cities in mainland France (Paris, Lyon and Marseille) and in one overseas city (Fort-de-France). The investigators will also describe the psychological and infectious comorbidities of drug users, determine the stages of the HCV (Hepatitis C Virus), HBV (Hepatitis B Virus), HIV (Human Immunodeficiency Virus) care cascade, and analyze the factors associated with HCV treatment failure. A qualitative study will investigate the acceptability of the RDS model. Participants will be screened in an out of bound research center and receive appropriate treatment for infectious, addictological and psychiatric troubles. They will receive coupons to give to their peers for them to participate in the study. Researchers will also compare the acceptability of referral to psychiatric care directly at the research site (intervention group) with that of referral directly to a city facility (control group).
Official title: Community Intervention to Eliminate HCV Among People Who Use Drugs. Implementation Study in the Cities of Paris, Marseille, Lyon and Fort-de-France, France.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
3400
Start Date
2023-10-02
Completion Date
2025-09-30
Last Updated
2025-09-08
Healthy Volunteers
Yes
Conditions
Interventions
Hybrid effectiveness-implementation study type 2
Diagnosis of hepatitis C; Assessment of hepatic fibrosis; Treatment of hepatitis C; Assessment of psychological disorders and treatment or referral.
Locations (4)
Lyon
Lyon, Auvergne-Rhône-Alpes, France
Marseille
Marseille, PACA, France
Paris
Paris, Île-de-France Region, France
Martinique
Fort-de-France, Martinique, Martinique