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Optimizing Mastitis Identification and Treatment
Sponsor: University of Tromso
Summary
The goal of this observational study is to gain more information about the aetiology and progression of mastitis and breast inflammation, in order to develop evidence-based clinical guidelines and treatment plans, especially concerning judicious use of antibiotics. The main questions it aims to answer are: * Do clinical symptoms differ between inflammatory and infectious mastitis? * What is the microbial composition in human milk, and does it change before, during, and after episodes of mastitis? * Does the bacterial composition change due to antibiotic treatment? * Are all mastitis episodes treated with antibiotics bacterial mastitis? * Do mothers with recurrent mastitis have a distinct microbial composition? * Are there immunological markers that can differentiate between bacterial and inflammatory mastitis? Researchers will compare breastfeeding women with and without mastitis to see if the microbiological composition in milk and on the skin of the breast and breast nipple differs.
Official title: OPTIMISTOptimizing Mastitis Identification and Treatment
Key Details
Gender
FEMALE
Age Range
18 Years - 50 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2023-10-01
Completion Date
2028-10-01
Last Updated
2026-03-12
Healthy Volunteers
No
Conditions
Locations (2)
Tromsø municipality, health centre
Tromsø, Troms, Norway
UiT-The Arctic University of Norway
Tromsø, Norway