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The RESCUE Study: Survival and Functional Outcomes Following Salvage Surgery for RESidual or reCurrent sqUamous cEll Carcinoma of the Head and Neck
Sponsor: Royal Marsden NHS Foundation Trust
Summary
The RESCUE study is a combined retrospective and prospective multicentre cohort study investigating the survival and functional outcomes in patients undergoing salvage surgery for recurrent, residual, and new primary head and neck squamous cell carcinoma (SCC). Additionally, the RESCUE study will contain an exploratory molecular analysis of consenting patients to assess the relationship between cancer genomics, previous radiotherapy, and recurrence in head and neck cancer.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2023-09-08
Completion Date
2029-04-30
Last Updated
2026-02-12
Healthy Volunteers
No
Conditions
Interventions
Molecular Analyses
Nucleic acid extraction, protein analysis. Tumour tissue, blood and saliva samples collected.
Locations (9)
University Hospitals Derby and Burton
Derby, United Kingdom
NHS Lothian
Edinburgh, United Kingdom
Western General, Greater Glasgow and Clyde
Glasgow, United Kingdom
Aintree Hospital
Liverpool, United Kingdom
Head and Neck Unit, Royal Marsden Hospital
London, United Kingdom
Northwick Park
London, United Kingdom
Oxford University Hospital NHS Foundation Trust
Oxford, United Kingdom
Poole Hospital, University Hospitals Dorset
Poole, United Kingdom
South Tyneside and Sunderland NHS Foundation Trust
Sunderland, United Kingdom