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RECRUITING
NCT05809284
Determining the Mechanisms of Loss of CAR T Cell Persistence
Sponsor: University College, London
View on ClinicalTrials.gov
Summary
A prospective observational study of pediatric and young adult acute lymphoblastic leukaemia (ALL) patients treated with CD19 chimeric antigen receptor T-cells (CAR-T cells). The study will examine changes in CAR-T persistence over time and causal factors.
Key Details
Gender
All
Age Range
Any - 25 Years
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2023-10-18
Completion Date
2025-12-01
Last Updated
2024-05-23
Healthy Volunteers
No
Conditions
Locations (3)
Great Ormond Street Hospital
London, United Kingdom
University College London Hospital
London, United Kingdom
Royal Manchester Children's Hospital
Manchester, United Kingdom