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Impact of an Early Identification Program for First-Episode Psychosis on the Duration of Untreated Psychosis
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Summary
The First-Episode Psychosis (FPE) is a severe disorder that can include delusions, cognitive disorders and suicidal behavior. In the majority of cases (more than 80%) it evolves into schizophrenia. Numerous studies show that the rapidity of the initial management of FPE would reduce the risk of negative evolution and would have a decisive impact on the short and long term prognosis. The rapidity of this management can be measured by the duration of untreated psychosis, or DUP (Duration of Untreated Psychosis), the time interval between the appearance of the first frank psychotic symptoms and the initiation of adequate psychiatric care. The objective of this study is to show the impact of an intervention facilitating access to specialized care for PEP on the reduction of DUP. This intervention consists of an early identification program for FPE, the PRESTO program, specifically targeting 3 determining steps in the reduction of DUP: * Informing the general population about psychotic disorders * Knowledge of front line actors (APL: general practitioners, school and university medicine, teenager's house, associative networks educators, emergency services, firefighters, etc.) about FPE and its management * Articulation between APL and specialized psychiatric care
Official title: Impact of an Early Identification Program for First-Episode Psychosis on the Duration of Untreated Psychosis. Multicenter, Randomized Stepped-wedge Study
Key Details
Gender
All
Age Range
15 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
416
Start Date
2023-06-06
Completion Date
2027-04
Last Updated
2025-11-24
Healthy Volunteers
No
Conditions
Interventions
PRESTO Early Identification Program
The program combines : 1. A population-based information component (information campaign aimed at the general population). 2. A training component for the LPAs (Front Line Actors: general practitioners, school and university medicine, pharmacists, teenagers school and university medicine, pharmacists, teenagers' homes, association networks, SAMU, firemen, etc.). 3. Facilitated access to care for FPE patients in the form of a "pivot" mobile team that can directly meet the patient at the request of the LPA, initiate care and ensure the relay within a the relay within 4 weeks to the existing specialized psychiatric structures on the site (CMP, CATTP (CMP, CATTP, day hospital, hospitalization unit, child and adolescent psychiatry services) adolescent psychiatry services)
Locations (6)
Hospices Civils de Lyon
Bron, France
Chu Clermont-Ferrand
Clermont-Ferrand, France
Chu Grenoble
Grenoble, France
CHU de Montpellier
Montpellier, France
CHU de Nîmes
Nîmes, France
Chu Saint Etienne
Saint-Etienne, France