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ACTIVE NOT RECRUITING
NCT05814705
NA

The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization

Sponsor: McMaster University

View on ClinicalTrials.gov

Summary

There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain foods can help reduce these declines. Recent research suggests that Urolithin A, which is a natural compound that can be produced after eating pomegranates, nuts, and berries, improves muscle health. In this study, the investigators aim to investigate if a protein beverage (standard care during disuse) with or without Urolithin A can reduce or prevent the loss of muscle health while wearing a knee brace (muscle disuse).

Official title: Comparison of High-protein Formulation With/Without Urolithin a During a Unilateral Knee Immobilization: a Pilot Proof-of-concept Trial

Key Details

Gender

MALE

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

24

Start Date

2023-06-01

Completion Date

2025-04-30

Last Updated

2024-10-02

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Protein supplement

Ready-to-drink protein beverage consumed once daily for 28 days

DIETARY_SUPPLEMENT

Protein supplement with Urolithin A

Ready-to-drink protein beverage with 1000 mg of Urolithin A consumed once daily for 28 days

Locations (1)

McMaster University

Hamilton, Ontario, Canada