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The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization
Sponsor: McMaster University
Summary
There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain foods can help reduce these declines. Recent research suggests that Urolithin A, which is a natural compound that can be produced after eating pomegranates, nuts, and berries, improves muscle health. In this study, the investigators aim to investigate if a protein beverage (standard care during disuse) with or without Urolithin A can reduce or prevent the loss of muscle health while wearing a knee brace (muscle disuse).
Official title: Comparison of High-protein Formulation With/Without Urolithin a During a Unilateral Knee Immobilization: a Pilot Proof-of-concept Trial
Key Details
Gender
MALE
Age Range
18 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2023-06-01
Completion Date
2025-04-30
Last Updated
2024-10-02
Healthy Volunteers
Yes
Conditions
Interventions
Protein supplement
Ready-to-drink protein beverage consumed once daily for 28 days
Protein supplement with Urolithin A
Ready-to-drink protein beverage with 1000 mg of Urolithin A consumed once daily for 28 days
Locations (1)
McMaster University
Hamilton, Ontario, Canada