Clinical Research Directory
Browse clinical research sites, groups, and studies.
Angiopoietin and Adverse Outcomes in Cardiac Surgery
Sponsor: Centre Hospitalier Universitaire, Amiens
Summary
Cardiac surgery and cardiopulmonary bypass can lead to systemic organ failure trough excess inflammation and endothelial injury. The angiopoietin family represented by angiopoietin 1 and 2 can reflect endothelial injury by a decrease in angiopoietin 1 and an increase in angiopoietin 2. The investigators hypothesized that angiopoietin dysregulation could reflect organ failure related to cardiac surgery. The purpose of this project is to assess the association between angiopoietin dysregulation and adverse outcomes on cardiac surgery.
Official title: Angiopoietin Dysregulation to Predict Adverse Outcomes in Cardiac Surgery: the Prospective
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2023-03-23
Completion Date
2027-04
Last Updated
2025-05-25
Healthy Volunteers
No
Conditions
Interventions
blood sample
5 ml blood sample will be withdrawn at the surgery start and at the surgery end
Locations (1)
CHU Amiens Picardie
Amiens, France