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Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen Planus
Sponsor: University of Catania
Summary
According to recent research, microRNAs (miRNAs) may function as early disease indicators and contribute to the severity of a number of precancerous and malignant oral disorders. The aim of the present study, through a double-blind randomized controlled trial design, is to analyze in the gingival crevicular fluid (GCF) as a non-invasive approach the impact of topical clobetasol on miRNAs expression in subjects affected by oral lichen planus (OLP).
Official title: Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen Planus: a Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2020-03-12
Completion Date
2023-08-10
Last Updated
2026-08-04
Healthy Volunteers
Yes
Conditions
Interventions
Clobetasol Topical Gel
Topic Clobetasol gel applied locally on OLP lesions.
Placebo
Placebo oral gel applied locally on OLP lesions.
Locations (1)
AOU Policlinico G. Rodolico
Catania, Catania, Italy