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"Principle Test" for Isolation and Characterization of Circulating Cancer Cells (CTC)-CXCR4+.
Sponsor: National Cancer Institute, Naples
Summary
This is multicentric, interventional, non farmacological and prospective study.
Official title: "Principle Test" for Isolation and Characterization of Cancer Cells (CTC)-CXCR4+ Circulating in Belotero Loaded With CXCL12 in Patients With Solid Neoplasms (Endometrium, Kidney, Glioblastoma, Colorectal, Ovary and Lung).
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
47
Start Date
2021-01-18
Completion Date
2025-12
Last Updated
2025-07-29
Healthy Volunteers
No
Conditions
Interventions
CLG
The development of an innovative device (CLG) consisting of an aqueous gel based on hyaluronic acid and commercially available (Belotero) able to be loaded and to release chemokine CXCL12 recreating a kind of "fake niche" able to attract immune cells- and CTCs-CXCR4+. The added value is the ability to attract and trap cells capable of leaking out and potentially with a higher metastatic capacity.
Locations (2)
Istitute Nazionale Tumori - Fondazione G. Pascale
Naples, Italy
Istituto Nazionale Tumori - Fondazione "G.Pascale", IRCCS
Naples, Italy