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Investigating Neural Biomarkers for Gait in Parkinson's Patients
Sponsor: Swiss Federal Institute of Technology
Summary
This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options. Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2023-04-13
Completion Date
2025-03
Last Updated
2024-12-03
Healthy Volunteers
Yes
Interventions
Neural Activity Recording
Neural Activity is measured using EEG in all groups. Additionally, in Parkinson's patients, local-field-potentials from deep brain stimulation electrodes are recorded.
Movement Parameter Recording
Gait-related movement parameters are non-invasively recorded using motion capture, accelerometers and electromyography.
Neuromodulation
Neural signals are recorded with the electrodes of the deep brain stimulation device. Parkinson's patients are asked to modulate their neural activity by observing the streamed neural activity and applying mental strategies.
Locations (1)
Cereneo
Vitznau, Canton of Lucerne, Switzerland