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What is Optimal Post-operative Prophylactic Therapy in Irradiated Breasts Undergoing Repeat Surgery
Sponsor: University of Alberta
Summary
This study will look at whether females who have previously had breast surgery and radiation and are undergoing repeat breast surgery require any post operative interventions. The reason the investigators are conducting this study is because females who have undergone breast radiation are at higher risk of wound complications following breast surgery. The investigators will randomize recruited female participants into three arms, one which is post operative antibiotics for one week, one which is a wound VAC, and one which is no intervention. The investigators goal is to identify whether these patients will require any postoperative interventions.
Official title: What is Optimal Post-operative Prophylactic Therapy in Irradiated Breasts Undergoing Repeat Oncologic Surgery to Reduce Early Wound Complications
Key Details
Gender
FEMALE
Age Range
18 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
105
Start Date
2023-06-26
Completion Date
2026-12-31
Last Updated
2025-09-05
Healthy Volunteers
Yes
Conditions
Interventions
TMP-SMX DS
Oral Antibiotic - used to treat post operative wound infections.
ciNPT dressing
Negative pressure wound VAC placed on incision post operatively.
Locations (2)
Meadowlark Health Centre
Edmonton, Alberta, Canada
St Thomas Surgical Clinic
St. Albert, Alberta, Canada