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RECRUITING
NCT05823467
NA

What is Optimal Post-operative Prophylactic Therapy in Irradiated Breasts Undergoing Repeat Surgery

Sponsor: University of Alberta

View on ClinicalTrials.gov

Summary

This study will look at whether females who have previously had breast surgery and radiation and are undergoing repeat breast surgery require any post operative interventions. The reason the investigators are conducting this study is because females who have undergone breast radiation are at higher risk of wound complications following breast surgery. The investigators will randomize recruited female participants into three arms, one which is post operative antibiotics for one week, one which is a wound VAC, and one which is no intervention. The investigators goal is to identify whether these patients will require any postoperative interventions.

Official title: What is Optimal Post-operative Prophylactic Therapy in Irradiated Breasts Undergoing Repeat Oncologic Surgery to Reduce Early Wound Complications

Key Details

Gender

FEMALE

Age Range

18 Years - 99 Years

Study Type

INTERVENTIONAL

Enrollment

105

Start Date

2023-06-26

Completion Date

2026-12-31

Last Updated

2025-09-05

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

TMP-SMX DS

Oral Antibiotic - used to treat post operative wound infections.

DEVICE

ciNPT dressing

Negative pressure wound VAC placed on incision post operatively.

Locations (2)

Meadowlark Health Centre

Edmonton, Alberta, Canada

St Thomas Surgical Clinic

St. Albert, Alberta, Canada