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ACTIVE NOT RECRUITING
NCT05828680

Circadian Rhythm Disruption in the Hospital Intensive Care Environment

Sponsor: University of Pennsylvania

View on ClinicalTrials.gov

Summary

Abrupt changes to one's lifestyle disrupt biorhythms. Acute effects are well known from jet lag where transmeridian travel leads to insomnia, fatigue, irritability, gastrointestinal symptoms and other complaints. Several studies in the hospital environment reported dampened and misaligned biorhythms, suggesting that the inpatient experience is replete with circadian disruptors. However, comprehensive assessments of how circadian clocks are affected in intensive care and how this predicts post-operative recovery and risk are largely missing.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

15

Start Date

2023-03-15

Completion Date

2028-12

Last Updated

2026-01-23

Healthy Volunteers

Not specified

Interventions

OTHER

Observation

No intervention

Locations (1)

Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania School of Medicine

Philadelphia, Pennsylvania, United States