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Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Sponsor: University of Florida
Summary
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain stimulation may be effective at restoring lost function. This study tests whether electrical stimulation of prefrontal brain regions is more beneficial than sham stimulation.
Official title: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2024-04-15
Completion Date
2027-04-30
Last Updated
2025-05-08
Healthy Volunteers
No
Interventions
Walking Exercise
aerobic walking exercise using complex (cognitively engaging) walking tasks
Prefrontal Active tDCS
20 minutes of 2 milliamp transcranial direct current stimulation (tDCS) of prefrontal regions, delivered at each session
Prefrontal Sham tDCS
30 seconds of 2 milliamp transcranial direct current stimulation (tDCS) of prefrontal regions, delivered at each session
Locations (2)
University of Florida
Gainesville, Florida, United States
Brooks Rehabilitation
Jacksonville, Florida, United States