Clinical Research Directory

Inclusion Criteria: * Newly diagnosed APL patients (WHO 2008 diagnostic classification); * 18-75 years old; * Liver function: propionate hydrogentransferase (ALT) and aspartate hydrogentransferase (AST) ≤ 2.5 times the upper limit of normal value, bilirubin ≤ 2 times the upper limit of normal value; * Renal function: muscle salt ≤ 3 times the upper limit of normal value; * The physical strength score is 0-2 (ECOG); * White blood cells ≤ 10×109/L; * Subjects must sign an informed consent form. Exclusion Criteria: * Subjects who have participated in other clinical trials within 30 days; * Pregnant and lactating subjects; * Subjects who are known to be HIV-positive in serological tests; * Subjects who have viral hepatitis serological test positive; * Subjects who have severe arrhythmia, abnormal electrocardiogram (QT\>500ms); * Subjects who suffer from mental illness or unable to cooperate with the research treatment and monitoring requirements due to other diseases; * Subjects who participate in other clinical research at the same time; * Subjects who fail to sign the informed consent form; * Other conditions that the researchers think are not suitable for inclusion.