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Mechanisms of Open and Hidden Placebo in Stroke Recovery
Sponsor: Spaulding Rehabilitation Hospital
Summary
This trial aims to investigate whether placebo in isolation (open and hidden) has a specific neural signature in stroke subjects thus providing a novel mechanism to explain placebo effects that can be used to ultimately enhance stroke rehabilitation therapies.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2023-09-11
Completion Date
2026-06-30
Last Updated
2025-09-17
Healthy Volunteers
No
Conditions
Interventions
Active rTMS
Subjects will undergo repetitive transcranial magnetic stimulation, each session lasting 20 minutes.
Sham rTMS
Subjects will undergo sham repetitive transcranial magnetic stimulation, each session lasting 20 minutes.
Open Placebo
The open placebo will consist of an inactive substance pill commonly used in clinical trials and given to the subject in a regular pill dispenser.
Locations (1)
Spaulding Hospital Cambridge
Cambridge, Massachusetts, United States