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Low-intensity Focused Ultrasound and Autonomic Response
Sponsor: Virginia Polytechnic Institute and State University
Summary
Studying the effects of Low Intensity Focused Ultrasound (LIFU) to the dorsal posterior insula (dPI) and dorsal anterior cingulate cortex (dACC) on autonomic control using a test to probe the autonomic system. A cold pressor task will be performed pre and post LIFU application. Physiologic recordings will be recorded throughout.
Official title: Investigation of Low-intensity Focused Ultrasound to the Salience Network on Autonomic Function
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-02-22
Completion Date
2026-12-30
Last Updated
2025-06-06
Healthy Volunteers
Yes
Conditions
Interventions
Low-intensity focused ultrasound neuromodulation
ultrasound transducer applying low intensity waveforms to targeted brain regions for neuromodulation.
Sham Low-intensity focused ultrasound
sham application of ultrasound using blocking of the ultrasound waves of the transducer.
Locations (1)
Fralin Biomedical Research Institute at VTC
Roanoke, Virginia, United States