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ENROLLING BY INVITATION
NCT05834829
NA

Low-intensity Focused Ultrasound and Autonomic Response

Sponsor: Virginia Polytechnic Institute and State University

View on ClinicalTrials.gov

Summary

Studying the effects of Low Intensity Focused Ultrasound (LIFU) to the dorsal posterior insula (dPI) and dorsal anterior cingulate cortex (dACC) on autonomic control using a test to probe the autonomic system. A cold pressor task will be performed pre and post LIFU application. Physiologic recordings will be recorded throughout.

Official title: Investigation of Low-intensity Focused Ultrasound to the Salience Network on Autonomic Function

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2024-02-22

Completion Date

2026-12-30

Last Updated

2025-06-06

Healthy Volunteers

Yes

Interventions

DEVICE

Low-intensity focused ultrasound neuromodulation

ultrasound transducer applying low intensity waveforms to targeted brain regions for neuromodulation.

DEVICE

Sham Low-intensity focused ultrasound

sham application of ultrasound using blocking of the ultrasound waves of the transducer.

Locations (1)

Fralin Biomedical Research Institute at VTC

Roanoke, Virginia, United States