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Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?
Sponsor: ART Fertility Clinics LLC
Summary
To investigate, whether on the day of egg retrieval, after ovarian stimulation for ICSI (intracytoplasmic sperm injection), there is a correlation between the intrafollicular AMH (Anti-Müllerian hormone) levels and the ploidy status of the blastocyst.
Official title: Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst? A Prospective Study
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2023-05-23
Completion Date
2026-12-31
Last Updated
2025-10-02
Healthy Volunteers
Yes
Conditions
Interventions
Oocyte Pick Up - Out of Study
Aspiration of follicles. search for the oocyte(s) All oocytes are grouped in one dish.
Denudation - Out of Study
All oocytes are denuded together. Maturational stages are recorded.
ICSI
One oocyte injected at a time.
Culture
One embryo per culture drop. Individual follow-up of the embryo development.
Biopsy
One embryo per culture drop.
Vitrification
One embryo per vitrification straw.
OPU - Study Group
Measure the size of the follicle and aspirate only one follicle and flush. The needle before moving to the second ovary. Oocyte included in the study will be cultured separately (each ovary separately too).
Denudation - Study Group
Oocyte included in the study will be denuded separately. Maturational stages are recorded per follicle.
Locations (1)
ART Fertility Clinics LLC
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates