Clinical Research Directory

Inclusion Criteria: * Male or female, between 20-70 years of age, who requests dental implant treatment option for rehabilitation. * Subjects who are willing to sign an informed consent, participate and return for follow-up visits. * Subjects without significant medical history and currently not on medications that might complicate our results. * Has a single-rooted tooth (upper and lower premolars to premolars) requiring extraction with two neighboring teeth on either side of it and intact bony walls. Exclusion Criteria: * Subjects who do not meet all the inclusion criteria or who will not cooperate with the protocol schedule. * Subjects who received and failed a previously placed dental implant. * Subjects who require additional ridge augmentation procedure in the area to achieve adequate bone volume for the placement of dental implants. * Subjects who have significant untreated periodontal disease, caries, infection or chronic inflammation in the oral cavity within two adjacent tooth positions of the clinical trial area. * Subjects who have used nicotine-containing products within 3 weeks prior to surgery. * Subjects who are insulin-dependent diabetic or if their Hgb1c levels \> 6.5%. * Subjects who have had a history of malignancy within the past 5 years (except for basal or squamous cell carcinoma of the skin or in situ cervical carcinoma). * Subjects who are nursing or pregnant. * Subjects who are presently taking medications (except estrogen/progesterone therapy) or those who are undergoing treatment that in known to have an effect on bone turnover. * Subjects who have diseases that affect bone metabolism (excluding idiopathic osteoporosis). * Subjects with a history of an autoimmune disease, documented allergy or multiple allergies to any component of the agents used in this study. * Difficult extraction with potential disruption / fracture of the alveolar bone. * Acutely infected defect site. * Subjects who are presently taking blood thinner medications.