Clinical Research Directory

Inclusion Criteria: * Male or female participants who are overtly healthy as determined by medical evaluation * Participants with body mass index (BMI) of 27.0 kilograms per meter squared (kg/m²) or more * Participants with a stable body weight, with 5% or less body weight gain or loss Exclusion Criteria: * Have any type of diabetes with hemoglobin A1c (HbA1c) level of 6.5% or greater or a fasting blood sugar over 120 milligram per deciliter (mg/dL) * Obesity induced by other endocrine disorders, such as Cushing's syndrome or Prader-Willi syndrome * Have known clinically significant gastric emptying abnormality * Have undergone bariatric surgery (for example: Lap-Band, Gastric Bypass) * Known self or family history (first-degree relative) of multiple endocrine neoplasia type 2A or type 2B, thyroid C-cell hyperplasia, or any form of thyroid cancer * Have significant previous or current history of comorbidities capable of significantly altering the absorption, metabolism, or elimination of drug * Have significant history of or currently have Major Depressive Disorder or psychiatric disorder within the last 2 years