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COMPLETED
NCT05841823
NA

Virtual Reality Exposure Therapy in the Treatment of Alcohol Use Disorder

Sponsor: Universiti Sains Malaysia

View on ClinicalTrials.gov

Summary

This study aims to compare the efficacy of virtual reality exposure therapy (VRET) with treatment-as-usual (TAU) for alleviating psychological dependence on alcohol and preventing relapse. It also assesses the changes of EEG in patients with alcohol use disorder after completion of the above related interventions. In this study 80 subjects with alcohol use disorder who have completed 2 weeks of in-patient detoxification will be randomized into two groups (VRET and treatment-as-usual control groups) and undergo respective interventions. Then assessment will be performed at four timelines (baseline, 4 weeks after baseline which is immediately after completion of intervention, 12 weeks after baseline, and 24 weeks after baseline assessment).

Official title: The Efficacy of Virtual Reality Exposure Therapy for the Treatment of Alcohol Use Disorder Among Adult Males: A Randomized Controlled Trial Comparing With Treatment-as-usual

Key Details

Gender

MALE

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2023-06-01

Completion Date

2024-06-30

Last Updated

2026-06-18

Healthy Volunteers

No

Interventions

BEHAVIORAL

Virtual reality exposure therapy (VRET)

The relaxation scene includes four beautiful landscapes, and patients can choose any of these four, as perceived to be the most comfortable landscape. The visual stimulation of high-risk scene is designed as any combination of four different scenes (street barbecue stands, restaurant, bar and home) and four kinds of alcoholic beverages (Chinese liquor, beer, grape wine and cocktail), which are customized according to the patient's personal preference. At the same time, the odor of the alcoholic beverage of the patient's choice will be provided as an olfactory stimulation. The aversive situation will be the visual and auditory stimulation provided by a video of an alcoholic vomiting, while olfactory stimulation will be provided by cotton balls soaked in fermented dairy products.

Locations (1)

Second Affiliated Hospital of Henan Medical University

Xinxiang, Henan, China