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ACTIVE NOT RECRUITING
NCT05842057
PHASE2

Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy

Sponsor: University of Miami

View on ClinicalTrials.gov

Summary

The purpose of this research study is to evaluate if placing a dehydrated human amnion chorion membrane (dHACM) over the nerves after removal of the prostate during surgery (radical prostatectomy) will allow an earlier recovery of erectile function and urinary control after surgery.

Official title: Phase 2 Randomized Trial: Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy (HAMMER)

Key Details

Gender

MALE

Age Range

40 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

118

Start Date

2023-08-24

Completion Date

2028-08-31

Last Updated

2025-07-22

Healthy Volunteers

No

Interventions

BIOLOGICAL

BioDFence G3 Placental Tissue Membrane

The BioDFence G3 Placental Tissue Membrane is a three-layer tissue allograft consisting of amnion-chorion-amnion. Amniotic membranes will be placed over the neurovascular bundle after extirpative RARP. The membrane will be cut into two longitudinal pieces and placed over each neurovascular bundle separately.

PROCEDURE

Robot-Assisted Radical Prostatectomy

Robot-assisted surgical removal of the prostate, administered standard of care.

Locations (1)

University of Miami

Miami, Florida, United States