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Liquid Biopsy Based NGS in Newly Diagnosed NSCLC
Sponsor: Charu Aggarwal
Summary
This study expands the application of an electronic health record (EHR) "nudge" used to prompt physicians' clinical practice to order molecular testing at the time of initial diagnosis for patients with specific types of advanced lung cancer. The primary goal is to have these test results available prior to starting treatment so that physicians can make molecularly-informed treatment decisions. The second goal is to better understand factors that contribute to whether or not the EHR-nudge implementation is successful.
Official title: iNUDGE: INtegration of liqUiD Biopsy Based Next Generation Gene sEquencing in Newly Diagnosed NSCLC - A Stepped Wedge Cluster Randomized Clinical Trial
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
260
Start Date
2023-06-15
Completion Date
2026-12-31
Last Updated
2026-03-11
Healthy Volunteers
No
Conditions
Interventions
iNUDGE
Electronic health record nudge which prompts physicians to order plasma-based NGS testing for eligible patients with newly diagnosed lung cancer.
Locations (6)
Penn Medicine Cherry Hill
Cherry Hill, New Jersey, United States
Penn Medicine Princeton Health
Plainsboro, New Jersey, United States
Penn Medicine Washington Township
Sewell, New Jersey, United States
Penn Medicine Voorhees
Voorhees Township, New Jersey, United States
Penn Medicine Lancaster General Health
Lancaster, Pennsylvania, United States
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, United States