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Stimulation-Induced Changes in Fronto-Limbic Network
Sponsor: University of Alabama at Birmingham
Summary
The purpose of this research is to better understand how emotion processing unfolds in the brain using stereoelectroencephalography (sEEG) and direct brain stimulation. This study will use standard behavioral emotion processing tasks combined with neural recording and direct brain stimulation to assess different aspects of emotion processing. Stimulation pulses during pre and post-test periods will assess the effects of stimulation before and after conditioning, the results of which will be combined with results from the activity of each electrode during the emotion tasks to inform us of the nature of emotion processing in the brain and allow us to devise brain modulation protocols in the future.
Official title: Stimulation-Induced Changes in Fronto-Limbic Connectivity Control Regulation of the Emotional Response to Threat
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2023-03-01
Completion Date
2027-04-30
Last Updated
2026-03-23
Healthy Volunteers
No
Conditions
Interventions
Electrical Pulse Train Stimulation
sEEG provides the ability to stimulate neural circuits via implanted electrodes by delivering mild intra-cranial electrical stimulations in different brain structures to estimate their impact on cognitive tasks.
Locations (1)
Epilepsy Monitoring Unit UAB Hospital
Birmingham, Alabama, United States