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Cardiometabolic Health in First Time Pregnancy
Sponsor: Cambridge University Hospitals NHS Foundation Trust
Summary
Women who experience placental complications (syndromes) during pregnancy, such as pre-eclampsia (high blood pressure and kidney problems), gestational hypertension (high blood pressure during pregnancy) and fetal growth restriction (baby being small) have twice the risk of developing heart disease and diabetes later in life, compared to women who have a healthy pregnancy. This study aims to assess risk factors for heart disease and diabetes in women who are actively trying to conceive, before and during their pregnancy, and 9-12 months after delivery of their baby, to see whether placental syndromes make a difference to their heart health. This will allow us to understand, if, and how, placental syndromes increase the risk of heart disease and diabetes, and, therefore, how best to reduce this risk and potentially prevent placental syndromes in the future. The investigators will also recruit women who are NOT planning pregnancy, as a control group.
Official title: Preconception to pOst-partum Study of Cardiometabolic Health in Primigravid PregnancY
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
OBSERVATIONAL
Enrollment
3500
Start Date
2023-05-24
Completion Date
2052-12
Last Updated
2024-04-09
Healthy Volunteers
Yes
Conditions
Locations (7)
Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom
NHS Greater Glasgow and Clyde
Glasgow, United Kingdom
University College London Hospitals NHS Foundation Trust
London, United Kingdom
King's College Hospital NHS Foundation Trust
London, United Kingdom
St George's University Hospitals NHS Foundation Trust
London, United Kingdom
Imperial College Healthcare NHS Trust
London, United Kingdom
Manchester University NHS Foundation Trust
Manchester, United Kingdom