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ACTIVE NOT RECRUITING
NCT05856357

Perennial Malaria Chemoprevention (PMC) in Côte D'Ivoire

Sponsor: London School of Hygiene and Tropical Medicine

View on ClinicalTrials.gov

Summary

The Plus Project will assess the impact, operational feasibility, efficacy, effectiveness, and cost-effectiveness of PMC. Specifically, the impact evaluation will involve monitoring a passive cohort of all children in the study area reporting all doses of SP received and the number of confirmed cases of malaria and anaemia, as well as a prospective active cohort of children who will have seven home visits over an 18-month period. The total number of participants is expected to be approximately 1568 children in the areas served by 19 health centres in Côte d'Ivoire. The results of this study will allow direct evaluation of the protective efficacy of PMC on malaria incidence, severe anaemia, and malaria mortality.

Official title: Impact Evaluation of Intermittent Preventive Treatment of Malaria in Infants Plus (IPTi+) in Côte D'Ivoire: the Plus Project

Key Details

Gender

All

Age Range

Any - 6 Months

Study Type

OBSERVATIONAL

Enrollment

1568

Start Date

2023-08-11

Completion Date

2025-09

Last Updated

2025-01-09

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Sulfadoxine pyrimethamine

Sulfadoxine-pyrimethamine paediatric formulation (250mg/12.5mg) dispersable tablets (Macleods Pharmaceuticals Ltd)

Locations (1)

Multiple

Séguéla, Côte d’Ivoire