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Perennial Malaria Chemoprevention (PMC) in Côte D'Ivoire
Sponsor: London School of Hygiene and Tropical Medicine
Summary
The Plus Project will assess the impact, operational feasibility, efficacy, effectiveness, and cost-effectiveness of PMC. Specifically, the impact evaluation will involve monitoring a passive cohort of all children in the study area reporting all doses of SP received and the number of confirmed cases of malaria and anaemia, as well as a prospective active cohort of children who will have seven home visits over an 18-month period. The total number of participants is expected to be approximately 1568 children in the areas served by 19 health centres in Côte d'Ivoire. The results of this study will allow direct evaluation of the protective efficacy of PMC on malaria incidence, severe anaemia, and malaria mortality.
Official title: Impact Evaluation of Intermittent Preventive Treatment of Malaria in Infants Plus (IPTi+) in Côte D'Ivoire: the Plus Project
Key Details
Gender
All
Age Range
Any - 6 Months
Study Type
OBSERVATIONAL
Enrollment
1568
Start Date
2023-08-11
Completion Date
2025-09
Last Updated
2025-01-09
Healthy Volunteers
Yes
Interventions
Sulfadoxine pyrimethamine
Sulfadoxine-pyrimethamine paediatric formulation (250mg/12.5mg) dispersable tablets (Macleods Pharmaceuticals Ltd)
Locations (1)
Multiple
Séguéla, Côte d’Ivoire