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ACTIVE NOT RECRUITING
NCT05857137
NA

Psychosis TMS Study

Sponsor: Massachusetts General Hospital

View on ClinicalTrials.gov

Summary

The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI. TMS is a noninvasive method used to modulate brain activity via changing magnetic fields applied over the surface of the scalp.

Official title: Investigational TMS Study of Cognitive Impairment in Early Psychosis

Key Details

Gender

All

Age Range

18 Years - 35 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2023-04-04

Completion Date

2026-07-30

Last Updated

2026-02-10

Healthy Volunteers

No

Conditions

Interventions

DEVICE

Active TMS

Continuous theta burst stimulation (cTBS) will be administered over the left inferior parietal lobule for approximately 3 minutes at 120% of the resting motor threshold.

DEVICE

Placebo TMS

Placebo TMS will be applied over the left inferior parietal lobule for approximately 3 minutes.

Locations (1)

Martinos Center for Biomedical Imaging

Charlestown, Massachusetts, United States