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Psychosis TMS Study
Sponsor: Massachusetts General Hospital
Summary
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI. TMS is a noninvasive method used to modulate brain activity via changing magnetic fields applied over the surface of the scalp.
Official title: Investigational TMS Study of Cognitive Impairment in Early Psychosis
Key Details
Gender
All
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2023-04-04
Completion Date
2026-07-30
Last Updated
2026-02-10
Healthy Volunteers
No
Conditions
Interventions
Active TMS
Continuous theta burst stimulation (cTBS) will be administered over the left inferior parietal lobule for approximately 3 minutes at 120% of the resting motor threshold.
Placebo TMS
Placebo TMS will be applied over the left inferior parietal lobule for approximately 3 minutes.
Locations (1)
Martinos Center for Biomedical Imaging
Charlestown, Massachusetts, United States