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Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery
Sponsor: Universidade Nova de Lisboa
Summary
Obesity and Type 2 diabetes mellitus (DMT2) are two of the most common chronic diseases of the Western society. Obesity is one critical factor in DMT2 development, with weight loss having profound beneficial effects on DMT2 and improving the metabolic pathophysiology leading to hyperglycemia. Observational studies reported that surgical intervention of morbid obesity achieved significant improvement of resolution of DMT2, both in short and long-term. Bariatric surgery has been considered the best option for treatment of diabetic obese patients, with the laparoscopic Roux-en-Y Gastric Bypass being the gold standard of the surgical treatment. Bariatric arterial embolization (BAE) technique has proved to be safe effective for weight loss in obese patients, but its metabolic effects have not been studied yet. The hypothesis of the study is that BAE is effective for the resolution of DMT2 inpatients with BMI between 30-43 Kg/m2. The aim is to assess DMT2 remission after BAE and bariatric surgery, to analyze potential conditioning factors, and to compare remission criteria between bariatric surgery and BAE.
Official title: Comparison of Metabolic Effects of Bariatric Arterial Embolization vs. Bariatric Surgery
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2021-06-16
Completion Date
2025-10
Last Updated
2024-12-11
Healthy Volunteers
Yes
Interventions
Roux-en-Y gastric By-pass (RYGB) surgery
RYGB procedure requires 1-2 hours of operating time and two to three days length of hospital stay. Use the Kit-RYGB by J\& company.
Bariatric Arterial Embolization (BAE) procedure
use of Embosphere Microspheres (EM) that are designed to offer controlled, target embolization.
Locations (1)
Cruz Vermelha Hospital
Lisbon, Portugal