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RECRUITING
NCT05862792

Liposomal Bupivacaine and Transoral Robotic Surgery

Sponsor: Geisinger Clinic

View on ClinicalTrials.gov

Summary

This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.

Official title: Impact of Liposomal Bupivacaine on Post-operative Pain, Opioid Use, and Swallow Function in Transoral Robotic Surgery

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

80

Start Date

2023-06-01

Completion Date

2026-01-15

Last Updated

2025-09-09

Healthy Volunteers

No

Interventions

DRUG

Liposomal bupivacaine

We will inject liposomal bupivacaine into the surgical bed.

Locations (1)

Geisinger Medical Center

Danville, Pennsylvania, United States