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PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis
Sponsor: Oregon Health and Science University
Summary
The purpose of the study is to learn more about the role of blood clotting factor proteins and cells in menstrual (period) bleeding. The investigators are hoping to identify differences in these proteins and cells in the menstrual blood of individuals with heavy periods compared to menstruating individuals who do not have heavy periods.
Official title: The Role of Plasminogen Activator Inhibitor-1 (PAI-1), Tissue Plasminogen Activator (tPA), Tissue Factor Pathway Inhibitor (TFPI), and Endometrial Endothelial Cells in Uterine Hemostasis in Humans
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2023-07-12
Completion Date
2026-07
Last Updated
2024-08-19
Healthy Volunteers
Yes
Conditions
Interventions
Sample Collection and Endometrial Biopsy
Participants will provide daily samples of menstrual blood for a single cycle and undergo a single endometrial biopsy for HEEC culture.
Locations (1)
OHSU
Portland, Oregon, United States