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A Study in Healthy Men to Test How BI 764198 is Processed in the Body
Sponsor: Boehringer Ingelheim
Summary
The main objective of this trial is to investigate the basic pharmacokinetics of BI 764198 and its metabolites, total radioactivity including mass balance, excretion pathways and metabolism following oral administration to healthy male volunteers of a single oral dose of BI 764198 (C-14) in i) a classical hADME approach and ii) a hADME microtracer approach.
Official title: A Phase I, Open-label, Two-arm, Non-randomised Trial to Investigate the Metabolism and Pharmacokinetics of a Single Dose of BI 764198 (C-14) Administered as Oral Solution Using Two Different Approaches in Healthy Male Volunteers
Key Details
Gender
MALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2023-05-03
Completion Date
2023-11-09
Last Updated
2026-06-29
Healthy Volunteers
Yes
Conditions
Interventions
BI 764198 (C-14) (approach 1)
BI 764198 (C-14) (approach 1)
BI 764198 (C-14) (approach 2)
BI 764198 (C-14) (approach 2)
Locations (1)
ICON
Groningen, Netherlands