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RECRUITING
NCT05867706

Caregiver Stress and Bereavement

Sponsor: University of Zurich

View on ClinicalTrials.gov

Summary

The death of a spouse is considered one of the most stressful and impactful life events and is associated with increased morbidity and premature mortality. Early identification of individuals who are most at risk for poor health outcomes following bereavement is an important aim of precision medicine and disease prevention initiatives. A better understanding of caregiver burden and bereavement-related distress and its implication for health is a clinically-relevant step toward the development of treatments that improve health outcomes in bereaved spouses. This study aims to map profiles of individual differences in short- and long-term adjustment to loss, according to psychological (e.g., depression, stress, grief severity) and biological markers (e.g., inflammation, cortisol) over time.

Official title: The Psychobiological Adjustment to Bereavement Among Cancer Caregivers

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

150

Start Date

2024-10-01

Completion Date

2027-12-31

Last Updated

2025-04-04

Healthy Volunteers

Yes

Locations (1)

University Hospital Zurich

Zurich, Canton of Zurich, Switzerland