Clinical Research Directory

Inclusion Criteria: * Patient aged ≥ 18 years. * Patient with clinically diagnosed atopic dermatitis according to the criteria of Hanifin and Rajka. * Moderate to severe defined by an Investigator's Global Assessment ³3 and eligible to systemic treatment. * If the subject is a woman of childbearing potential, she has a negative urine pregnancy test. * Subject is non-pregnant, non-lactating and is not planning for pregnancy during the study period. * Subject is in good general health and free of any known disease state or physical condition which, in the investigator's opinion, might impair his/her evaluation or which exposes the subject to an unacceptable risk by study participation. * Subject is able to comprehend and willing to sign an Informed Consent and/or Assent Form. * Affiliation to a social security scheme. * Signed informed consent Exclusion Criteria: * Vulnerable person: pregnant or nursing woman, minor, adult under guardianship or deprived of liberty * Patient with an infection * Patient with other systemic inflammatory disease * Patient with anti-inflammatory or immunosuppressive therapy * Patient with a contraindication to JAK inhibitors * Participants in other clinical therapeutic studies involving a drug that may interfere with the present evaluation