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RECRUITING
NCT05869760

Baylor Infant and Toddler Biomarker of Nutrition Study

Sponsor: Baylor College of Medicine

View on ClinicalTrials.gov

Summary

Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals. In addition to nutrients, there are substances in fruits, vegetables, milk and formula, called phytochemicals, that can support health. While researchers know more about the role of phytochemicals in adult health, researchers know surprisingly little about how phytochemicals can support health in young children. One group of phytochemicals are called the carotenoids. Carotenoids are responsible for the red, orange, and yellow colors in some fruits and vegetables. In adults, carotenoids can support visual function. Researchers also know that measuring levels of carotenoids in the blood or optically in the skin, can serve as an indirect measurement of what child and adults eat. The purpose of this study is to determine how a child's usual intake of carotenoids is related to their visual development and their blood and skin levels of carotenoids. The study involves 6 visits. For each visit, we will ask about the child's recent diet, will measure their body size, collect a blood sample, collect optical measurements of their skin, and will test how sharp their vision is.

Official title: Observational Validation of Skin Carotenoid Biomarker of Infant and Toddler Carotenoid Intake

Key Details

Gender

All

Age Range

3 Months - 24 Months

Study Type

OBSERVATIONAL

Enrollment

208

Start Date

2023-06-26

Completion Date

2028-11-30

Last Updated

2026-03-27

Healthy Volunteers

Yes

Interventions

OTHER

Carotenoid Intake

Carotenoid intake calculated from food diary records reported by guardians.

OTHER

Serum carotenoid concentrations

Serum carotenoid concentrations measured by HPLC.

Locations (1)

USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine

Houston, Texas, United States