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ACTIVE NOT RECRUITING
NCT05871489

Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment Regimens

Sponsor: Harvard Medical School (HMS and HSDM)

View on ClinicalTrials.gov

Summary

This is a multisite prospective cohort study of patients with multidrug- or rifampin-resistant tuberculosis who are treated with an all-oral shortened regimen under routine program conditions in one of three countries (Peru, Lesotho, Kazakhstan).

Official title: Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment Regimens Through Improved Epidemiologic Methods

Key Details

Gender

All

Age Range

0 Years - 120 Years

Study Type

OBSERVATIONAL

Enrollment

800

Start Date

2020-09-22

Completion Date

2025-12-31

Last Updated

2024-12-05

Healthy Volunteers

No

Interventions

DRUG

Bdq, Lzd, Lfx, Dlm, Cfz (9-12 months)

Bdq, Lzd, Lfx, Dlm, Cfz for nine months, with extension to 12 months as needed

DRUG

Bdq, Lzd, Lfx, Cfz, Cs (9-12 months)

Bdq, Lzd, Lfx, Cfz, Cs for nine months, with extension to 12 months as needed

DRUG

Bdq, Lzd, Lfx, Z, Dlm (9-12 months)

Bdq, Lzd, Lfx, Z, Dlm for nine months, with extension to 12 months as needed

Locations (3)

Partners In Health, Kazakhstan

Almaty, Kazakhstan

Partners In Health, Lesotho

Maseru, Lesotho

Socios En Salud

Lima, Lima Province, Peru