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Biological Sample Repository for Gastrointestinal Disorders
Sponsor: Pichamol Jirapinyo, MD, MPH
Summary
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients presenting with short- and long-term surgical complications. The aim is to enhance the overall understanding of the mechanisms leading to obesity, weight loss, failure to lose weight, and weight regain following treatment. Additional goals are to determine the efficacy of endoscopic and surgical procedures, to identify potential therapeutic targets and disease biomarkers that predict response to therapy.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2023-07-19
Completion Date
2029-04
Last Updated
2025-12-02
Healthy Volunteers
No
Conditions
Interventions
Blood Collection
Blood collection via venipuncture
Urine Collection
Free catch urine sample collection
Tissue Sample Collection
Tissue (gastric, duodenum, jejunum and ileum - number of biopsies will be 3-4 from each site, ranging in size from 4-7mm) - These samples collected will be extra biopsies that are taken for research purposes during a clinically planned endoscopy for which biopsies are being planned.
Locations (1)
Brigham and Women's Hospital
Boston, Massachusetts, United States