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ACTIVE NOT RECRUITING
NCT05874726

Biological Sample Repository for Gastrointestinal Disorders

Sponsor: Pichamol Jirapinyo, MD, MPH

View on ClinicalTrials.gov

Summary

The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients presenting with short- and long-term surgical complications. The aim is to enhance the overall understanding of the mechanisms leading to obesity, weight loss, failure to lose weight, and weight regain following treatment. Additional goals are to determine the efficacy of endoscopic and surgical procedures, to identify potential therapeutic targets and disease biomarkers that predict response to therapy.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

500

Start Date

2023-07-19

Completion Date

2029-04

Last Updated

2025-12-02

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Blood Collection

Blood collection via venipuncture

DIAGNOSTIC_TEST

Urine Collection

Free catch urine sample collection

DIAGNOSTIC_TEST

Tissue Sample Collection

Tissue (gastric, duodenum, jejunum and ileum - number of biopsies will be 3-4 from each site, ranging in size from 4-7mm) - These samples collected will be extra biopsies that are taken for research purposes during a clinically planned endoscopy for which biopsies are being planned.

Locations (1)

Brigham and Women's Hospital

Boston, Massachusetts, United States