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RECRUITING
NCT05874921

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

Sponsor: UroGen Pharma Ltd.

View on ClinicalTrials.gov

Summary

The purpose of this registry is to evaluate real world experience and outcomes of patients with Upper Tract Urothelial Cancer (UTUC) treated with Jelmyto in the United States.

Official title: uTRACT Jelmyto Registry: A Multicenter, Prospective and Retrospective Registry to Evaluate Real World Experience and Outcomes of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

400

Start Date

2023-11-17

Completion Date

2028-01

Last Updated

2025-02-28

Healthy Volunteers

No

Interventions

DRUG

Jelmyto (mitomycin) for pyelocalyceal solution

The dose of Jelmyto to be instilled is 4 mg per mL via ureteral catheter or a nephrostomy tube, with total instillation volume based on volumetric measurements using pyelography, not to exceed 15 mL (60 mg of mitomycin). Instill Jelmyto once weekly for six weeks. For patients with a complete response 3 months after Jelmyto initiation, Jelmyto instillations may be administered once a month for a maximum of 11 additional instillations.

Locations (22)

Providence St. Johns Health Center

Santa Monica, California, United States

University of Florida

Gainesville, Florida, United States

Mount Sinai Medical Center of Florida, Inc.

Miami, Florida, United States

H. Lee Moffitt Cancer Center and Research Institute Hospital, Inc.

Tampa, Florida, United States

Northwestern University

Chicago, Illinois, United States

Indiana University

Indianapolis, Indiana, United States

The State University of Iowa

Iowa City, Iowa, United States

Chesapeake Urology

Baltimore, Maryland, United States

Johns Hopkins Medical Center

Baltimore, Maryland, United States

Mass General Hospital (MGH)

Boston, Massachusetts, United States

The Brigham and Womens Hospital

Boston, Massachusetts, United States

University of Michigan

Ann Arbor, Michigan, United States

University of Missouri

Columbia, Missouri, United States

Rutgers

New Brunswick, New Jersey, United States

The Feinstein Institutes for Medical Research

Lake Success, New York, United States

NYU Grossman School of Medicine

New York, New York, United States

SUNY Upstate

Syracuse, New York, United States

The University of North Carolina Chapel Hill

Chapel Hill, North Carolina, United States

Ohio State University

Columbus, Ohio, United States

Medical University of South Carolina

Charleston, South Carolina, United States

UT Southwestern Medical Center

Dallas, Texas, United States

The University of Texas M.D. Anderson Cancer Center

Houston, Texas, United States