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First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors
Sponsor: Daiichi Sankyo
Summary
This study will evaluate the safety, tolerability, and efficacy of DS-3939a in participants with advanced solid tumors.
Official title: Phase 1/2, Open-label, Multicenter, First-in-Human Study of DS-3939a in Subjects With Advanced Solid Tumors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
590
Start Date
2023-08-18
Completion Date
2027-02-15
Last Updated
2026-09-29
Healthy Volunteers
No
Interventions
DS-3939a
One IV infusion Q3W on Day 1 of each 21-day cycle
Locations (61)
Florida Cancer Specialists
Sarasota, Florida, United States
Florida Cancer Specialists
Sarasota, Florida, United States
Piedmont Cancer Institute
Locust Grove, Georgia, United States
University of Kansas Medical Center
Westwood, Kansas, United States
Henry Ford Health System
Detroit, Michigan, United States
Astera Cancer Care
East Brunswick, New Jersey, United States
Icahn School of Medicine Mt Sinai
New York, New York, United States
Oregon Health & Science University
Portland, Oregon, United States
Rhode Island Hospital
Providence, Rhode Island, United States
University of Texas M.D. Anderson Cancer Center
Houston, Texas, United States
Huntsman Cancer Institute, University of Utah
Salt Lake City, Utah, United States
Virginia Cancer Specialists
Fairfax, Virginia, United States
The Medical College of Wisconsin, INC
Milwaukee, Wisconsin, United States
The Medical College of Wisconsin, INC
Milwaukee, Wisconsin, United States
UZ Leuven
Leuven, Belgium
McGill University Health Center
Montreal, Canada
Princess Margaret Cancer Center
Toronto, Canada
Beijing Cancer Hospital
Beijing, China
Jilin Cancer Hospital
Changchun, China
Hunan Cancer Hospital
Changsha, China
Sichuan Cancer Hospital
Chengdu, China
Zhejiang Cancer Hospital
Hangzhou, China
Shandong Cancer Hospital
Jinan, China
The First Affiliated Hospital of Nanchang University
Nanchang, China
The Second Peoples Hospital of Neijiang
Neijiang, China
Shanghai East Hospital
Shanghai, China
Tianjin Medical University Cancer Institute & Hospital
Tianjin, China
Union Hospital of Tongji Medical College, Huazhong University of Science and Technology
Wuhan, China
The First Affiliated Hospital of Xiâ An Jiaotong University
Xi'an, China
Xiangyang Central Hospital
Xiangyang, China
Centre Léon Bérard
Lyon, France
Centre Léon Bérard
Lyon, France
Assistance Publique- de Marseille
Marseille, France
Ico - Site René Gauducheau
Saint-Herblain, France
Chu Strasbourg
Strasbourg, France
Institut Claudius Regaud
Toulouse, France
Institut Claudius Regaud
Toulouse, France
Institut Gustave Roussy
Villejuif, France
National Cancer Center Hospital
Chūōku, Japan
Kansai Medical University Hospital
Hirakata-shi, Japan
National Cancer Center Hospital East
Kashiwa, Japan
Cancer Institute Hospital of Jfcr
Kōtoku, Japan
Saiseikai Kumamoto Hospital
Kumamoto, Japan
Osaka International Cancer Institute
Osaka, Japan
Kindai University Hospital
Ōsaka-sayama, Japan
Nho Hokkaido Cancer Center
Sapporo, Japan
Sendai Kousei Hospital
Sendai, Japan
Shizuoka Cancer Center
Sunto-gun, Japan
National Cancer Center
Goyang, South Korea
Seoul National University Bundang Hospital
Seongnam-si, South Korea
Seoul National University Hospital
Seoul, South Korea
Severance Hospital, Yonsei University Health System
Seoul, South Korea
Asan Medical Center
Seoul, South Korea
Samsung Medical Center
Seoul, South Korea
Hospital Universitari Vall D'Hebron
Barcelona, Spain
Hospital Universitario Ramon Y Cajal
Madrid, Spain
Hospital Universitario 12 de Octubre
Madrid, Spain
Hospital Universitario La Paz
Madrid, Spain
Hospital Regional Universitario de Malaga
Málaga, Spain
Next Madrid
Pozuelo de Alarcón, Spain
Hospital Universitario Virgen Macarena
Seville, Spain