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Low-dose Contrast Media for Low-kVp Abdomen CT
Sponsor: Bohyun Kim
Summary
The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients. The main questions to be answered are: 1, Can low-dose contrast media paired with low-dose radiation CT of the abdomen provide acceptable diagnostic accuracy in acute appendicitis? 2. How much radiation dose can be saved by using low radiation dose abdominal CT in combination with low dose contrast media?
Official title: Optimizing Low-dose Contrast Media Protocol for Low-kVp Abdominopelvic CT in Suspected Acute Appendicitis
Key Details
Gender
All
Age Range
19 Years - 44 Years
Study Type
INTERVENTIONAL
Enrollment
292
Start Date
2023-12-21
Completion Date
2025-12-31
Last Updated
2025-05-28
Healthy Volunteers
No
Conditions
Interventions
Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
The investigators are aiming for a 10% reduction in iodine dosage at 10 kVp reduction in CT radiation. Routine iodine dosing is 0.521 g I/kg at 120 kVp. Therefore, at 90 kVp, a 30% reduction in iodine dosing is expected, which is 0.365 g I/kg. At 100 kVp, the iodine dosage is reduced to 0.417 g I/kg, which is a 20% reduction. The kVp value is automatically selected by the CT device according to the body habitus, which is a clinical routine.
Locations (1)
Seoul St. Mary's Hospital
Seoul, South Korea