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RECRUITING
NCT05880043
PHASE1/PHASE2

GIC-102, Intravenous Allogeneic NK Cells, in Subjects With Advanced Solid Cancers and R/R Hematologic Malignancies

Sponsor: GI Cell, Inc.

View on ClinicalTrials.gov

Summary

This is a first-in-human trial to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor effects of GIC-102 in patients with advanced solid tumors, relapsed/refractory non-hodgkin lymphoma, and multiple myeloma.

Official title: An Open-label, Multi-center, Dose-escalation and Expansion, Phase 1/2a Study to Evaluate the Safety, Tolerability, PK/PD, and Preliminary Anti-tumor Activity of GIC-102 Monotherapy in Patients With Advanced Solid Tumors, R/R Non-Hodgkin Lymphoma, and Multiple Myeloma

Key Details

Gender

All

Age Range

19 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2023-04-28

Completion Date

2026-06-30

Last Updated

2024-07-09

Healthy Volunteers

No

Interventions

DRUG

GIC-102

GIC-102 will be administered via IV infusion 3 times at intervals of 1 week, and 28 days is defined as 1 cycle

DRUG

GIC-102

GIC-102 will be administered via IV infusion 3 times at intervals of 1 week, and 28 days is defined as 1 cycle

Locations (4)

Korea University Anam Hospital

Seoul, South Korea

Seoul Asan Medical center

Seoul, South Korea

Seoul Asan Medical center

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea