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Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Sponsor: VA Office of Research and Development
Summary
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on physical functioning, health-related quality of life, and adipose tissue inflammatory and cellular senescence profiles in older Veterans. Further, it will evaluate whether a weight loss intervention, including dietary modification and exercise, in obese Veterans with and without PCC will reduce systemic and adipose tissue inflammation and senescence and promote PCC recovery.
Key Details
Gender
All
Age Range
Any - 80 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-06-03
Completion Date
2028-09-30
Last Updated
2025-06-29
Healthy Volunteers
Yes
Conditions
Interventions
12-weeks of Weight Loss
Participants will be asked to participate in a 1x/week center-based or tele-health nutrition diet class, 2x/week center-based exercise classes, and 1x/week exercise session conducted on their own for \~12 weeks.
12-weeks of Weight Stability
Participants will be asked to participate in a 1x/week center-based or tele-health education class, 2x/week center-based stretching/balance classes, and 1x/week stretching/balance session conducted on their own for \~12 weeks.
Locations (2)
Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD
Baltimore, Maryland, United States
South Texas Health Care System, San Antonio, TX
San Antonio, Texas, United States